Progesterone secretion during pregnancy in sheep with an autotransplanted adrenal and an autotransplanted ovary
- 1 September 1978
- journal article
- research article
- Published by Bioscientifica in Reproduction
- Vol. 54 (1), 153-157
- https://doi.org/10.1530/jrf.0.0540153
Abstract
Secretion rates by the major sites of progesterone synthesis were measured during pregnancy in 3 ewes with single fetuses after autotransplantation of the left adrenal and the left ovary (containing the corpus luteum) to the neck. The total production of progesterone measured by tracer kinetics increased from 12.1 .+-. 2.0 [standard error of the mean] to 31.3 .+-. 2.4 .mu.g/min between 66-103 and 133-145 days post coitum. Ovarian and adrenal secretion rates measured directly at the same times decreased from 5.2 .+-. 0.9 to 2.1 .+-. 0.9 .mu.g/min (ovary), or remained unchanged, about 0.03 .mu.g/min (adrenal). The difference between the total production of progesterone and ovarian and adrenal secretion showed that the contribution from other endocrine tissues (presumably the placenta) increased from 6.8 .+-. 1.5 to 29.2 .+-. 4.1 .mu.g/min (P < 0.001) during this period.This publication has 2 references indexed in Scilit:
- A COMPARISON OF PROGESTERONE METABOLISM IN THE PREGNANT SHEEP AND GOAT: SOURCES OF PRODUCTION AND AN ESTIMATION OF UPTAKE BY SOME TARGET ORGANSJournal of Endocrinology, 1968
- THE STUDY OF OVARIAN FUNCTION IN THE EWE BY MEANS OF A VASCULAR AUTOTRANSPLANTATION TECHNIQUEJournal of Endocrinology, 1967