Human mammary and bronchial carcinomas. In vivo and in vitro secretion of substances immunologically cross‐reactive with insulin
- 29 June 1984
- Vol. 53 (11), 2467-2471
- https://doi.org/10.1002/1097-0142(19840601)53:11<2467::aid-cncr2820531117>3.0.co;2-#
Abstract
In the blood of 2 patients suffering from mammary carcinoma and 1 from bronchial carcinoma, the levels of substances immunologically cross-reactive with insulin (SICRI) were high before surgery; after surgery normoinsulinemia was restored. Direct evidence of SICRI production by the cultured tumorous tissues is presented. Strong daily SICRI fluctuations were observed, and it is proposed that the fluctuations induce instantaneous hypoglycemias experienced by some tumorous patients.This publication has 16 references indexed in Scilit:
- C-peptide does not parallel increases of serum levels of substances immunologically cross-reactive with insulin in non-Hodgkin's lymphoma patientsBlood, 1983
- Correlation of substance(s) immunologically cross-reactive with insulin, glucose and growth hormone in Hodgkin lymphoma patientsCancer Letters, 1982
- SOMATOSTATIN-REDUCED PROLIFERATION OF MURINE APLASTIC CARCINOMA CONDITIONED TO DIABETESInternational Journal of Cancer, 1982
- Paraneoplastic syndromesEuropean Journal of Cancer and Clinical Oncology, 1981
- Insulin and glucagon secretion by renal adenocarcinomaCancer, 1981
- INSULIN LEVELS IN HODGKIN'S DISEASEBritish Journal of Haematology, 1980
- Immunoassayable insulin in carcinoma of the cervix associated with hypoglycemiaCancer, 1973
- Insulin-secreting bronchial carcinoid tumor with widespread metastasesAmerican Journal Of Medicine, 1968
- Immunoassay of Insulin: Two Antibody System: Plasma Insulin Levels of Normal, Subdiabetic and Diabetic RatsDiabetes, 1963
- A FIBROSARCOMA WITH HYPOGLYCÆMIA AND A HIGH SERUM-INSULIN LEVELThe Lancet, 1962