Frozen Blood

Abstract

THIS article reviews developments in the long-term preservation of human red cells with the use of freezing technics. The discussion is concerned primarily with the safety and efficacy of the biologic product resulting from each of the current processes, which differ markedly in the stage of their clinical evaluation. By design, the review excludes consideration of much background material in the nature of the physicochemical phenomena of freezing and in vitro experimentation that is not directly related to clinical situations. Details of this background information may be obtained from some of the principal references cited and from other reviews.^{1 , 2} It . . .