The mechanism of replication of hepatitis B virus: Evidence of asymmetric replication of the two DNA strands
- 1 January 1984
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 13 (1), 83-91
- https://doi.org/10.1002/jmv.1890130110
Abstract
In this study we have characterised the DNA replicative intermediates of hepatitis B virus and have shown that HBV-DNA replication is asymmetric. This pattern of HBV replication is similar to that reported for the related duck hepatitis virus (DHBV) and suggests the involvement of a similar reverse transcription process in HBV-DNA replication.Keywords
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