ACTIVE SUPPRESSION OF INVITRO REACTIVITY OF SPLEEN-CELLS AFTER BCG TREATMENT
- 1 January 1978
- journal article
- research article
- Vol. 34 (3), 431-437
Abstract
Spleen cells from mice injected i.v. with large doses of BCG respond to PHA [phytohemagglutinin] stimulation less intensely than do normal spleen cells. Nylon wool column purified BCG treated T [thymus-derived] cells also had a low PHA reactivity. Unfractionated spleen cells, adherent cells or T-enriched populations from BCG treated mice, when added to normal T cells, lowered their PHA reactivity. When the same BCG treated cell populations were added to tumor cells in vitro, they inhibited their growth.This publication has 12 references indexed in Scilit:
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