A clinically significant interaction between ciprofloxacin and theophylline
- 1 January 1987
- journal article
- research article
- Published by Springer Nature in European Journal of Clinical Pharmacology
- Vol. 33 (4), 435-436
- https://doi.org/10.1007/bf00637645
Abstract
We report a case of theophylline toxicity following the co-administration of ciprofloxacin. Total theophylline clearance fell from 2.3 l·h−1 to 0.8 l·h−1 when ciprofloxacin was added to the treatment regimen and returned to 2.1 l·h−1 after ciprofloxacin was discontinued.This publication has 5 references indexed in Scilit:
- Effect of multiple dose oral ciprofloxacin on the pharmacokinetics of theophylline and indocyanine greenJournal of Antimicrobial Chemotherapy, 1987
- The influence of quinolone derivatives on theophylline clearance.British Journal of Clinical Pharmacology, 1986
- Treatment of respiratory tract infections with ciprofloxacinJournal of Antimicrobial Chemotherapy, 1986
- QUINOLONES AND RAISED PLASMA CONCENTRATIONS OF THEOPHYLLINEThe Lancet, 1984
- OPT: a package of computer programs for parameter optimisation in clinical pharmacokinetics.British Journal of Clinical Pharmacology, 1982