Anomeric Specificity of Glucose-Stimulated Insulin Release: Evidence for a Glucoreceptor?
- 8 November 1974
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 186 (4163), 536-538
- https://doi.org/10.1126/science.186.4163.536
Abstract
The effects on insulin secretion of α and β anomers of D-glucose were studied in the in vitro perfused rat pancreas. Both phases of insulin release showed consistent stereospecificity for α-glucose; this specificity indicates an action of glucose independent of intracellular glucose metabolism.Keywords
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