Characterization of Vitamin K from Human Liver
- 1 March 1972
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 102 (3), 331-335
- https://doi.org/10.1093/jn/102.3.331
Abstract
Preparative purification of natural vitamin K from human liver was accomplished by extraction, chromatography on silicic acid, extraction with Claisen's alkali, and several additional chromatographic methods. Ultraviolet absorption and mass spectrometry of the purified samples supported the presence of phylloquinone, MK-7, MK-8, MK-9, MK-9(H2), MK-9(H4), MK-10, MK-10(H2), MK-10(H4), and MK-11. The principal vitamins were phylloquinone and MK-7.Keywords
This publication has 8 references indexed in Scilit:
- Characterization of vitamin K from pig liver and dog liverArchives of Biochemistry and Biophysics, 1971
- Identification of phylloquinone in horse liverArchives of Biochemistry and Biophysics, 1970
- Bioassay of Vitamin K by Intracardial Injection in Deficient Adult Male RatsJournal of Nutrition, 1968
- Dose response and minimal daily requirement for vitamin K in man.Journal of Applied Physiology, 1967
- The Vitamin K Content of Beef Liver. Detection of a New Form of Vitamin K*Biochemistry, 1967
- Separation of vitamin K and associated lipids by reversed-phase partition column chromatographyAnalytical Biochemistry, 1967
- Resorption, Retention, Ausscheidung und Verteilung von PhyllochinonMenachinon‐4 und α‐Tocopherolchinon im Vergleich zum α‐Tocopherol bei der RatteHelvetica Chimica Acta, 1966
- Synthesis of Vitamin K1Journal of the American Chemical Society, 1939