The N‐terminus of amine oxidase of Hansenula polymorpha contains a peroxisomal targeting signal
- 3 January 1995
- journal article
- Published by Wiley in FEBS Letters
- Vol. 357 (2), 115-120
- https://doi.org/10.1016/0014-5793(94)01317-t
Abstract
Here we describe the identification of the targeting sequence of peroxisomal amine oxidase (AMO) of H. polymorpha. Deletion analysis revealed that essential targeting information is located within the extreme N-terminal 16 amino acids. Moreover, this sequence can direct a reporter protein to the peroxisomal matrix of H. polymorpha. The N-terminal 16 amino acids of AMO contain a sequence with strong homology to the conserved PTS2 sequence. Therefore, AMO is considered to be a PTS2 proteinKeywords
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