RELATIONSHIP OF DIURNAL VARIATION IN 17-HYDROXYCORTICOSTEROID LEVELS IN BLOOD AND URINE TO EOSINOPHILS AND ELECTROLYTE EXCRETION*

Abstract
Measurements of 17, 21 dihydroxy 20 ketosteroids were made in 25 normal subjects and a significant diurnal variation in blood and urine found. Additional measurements were made on 4 subjects on constant food and water intake every 3 hours. In these subjects eosinophil variations were closely related to plasma 17-oH-CS levels. A close relation between 17-oH-CS and K excretion was also found. However, Na excretion was not always associated with 17-oH-CS changes.