Neutron activation analysis for copper in biological material applied to Wilson's disease
Open Access
- 1 January 1968
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 21 (1), 8-11
- https://doi.org/10.1136/jcp.21.1.8
Abstract
A method for the neutron activation analysis of copper in biological material is described and applied to the diagnosis and management of four cases of Wilson's disease. Results obtained for serum and urine are in agreement with values obtained by established colorimetric techniques. The method described can estimate 10−9 g. copper to within 10% and this sensitivity has allowed the determination of copper from biopsy material such as liver, spleen, hair, and nail.This publication has 4 references indexed in Scilit:
- An absorptiometric method for the determination of traces of copper in biological materials with dithizoneClinica Chimica Acta; International Journal of Clinical Chemistry, 1965
- COPPER CONTENT OF HAIR AND NAILS IN WILSONS DISEASE (HEPATOLENTICULAR DEGENERATION)1961
- Simple procedure for the single sample determination of serum copper and ironClinica Chimica Acta; International Journal of Clinical Chemistry, 1958
- Abnormalities of Copper Metabolism in Wilson's Disease and Their Relationship to the AminoaciduriaJournal of Clinical Investigation, 1954