Squamous Cell Carcinoma of the Bladder

Abstract

Medical and surgical pathological records were analyzed for 46 patients with pure squamous cell carcinoma of the bladder. Nine patients had metastatic disease at the time of presentation; the remainder had disease limited to the bladder. The 5-yr survival figures were 37% for patients with submucosal and/or muscular invasion and 13% for those with perivesical invasion. No patient with extravesical disease survived 5 yr. The best survival figures were encountered in patients who had preoperative radiation therapy followed by total cystectomy and urinary diversion compared to other modalities of treatment. Preoperative radiation therapy followed by cystectomy and urinary diversion is recommended as the treatment of choice for patients with this uncommon bladder neoplasm.