Ganglioside monoclonal antibody (A2B5) labels Alzheimer's neurofibrillary tangles
- 1 May 1987
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 37 (5), 768
- https://doi.org/10.1212/wnl.37.5.768
Abstract
Ganglioside monoclonal antibody (A2B5) labels Alzheimer's neurofibrillary tangles both in isolated neurofibrillary tangle-bearing nerve cells and in partially purified preparations of tangle fibers. Antibody staining was preab-sorbed by preincubation of antibody with neuronal ganglioside preparations. These results suggest that Alzheimer's neurofibrillary tangles have a ganglioside associated with them.This publication has 10 references indexed in Scilit:
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