Corticosteroid 21-sulphates in human urine
- 1 October 1961
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 81 (1), 147-149
- https://doi.org/10.1042/bj0810147
Abstract
After administration of 300 mg. of cortlcosterone or cortlsol to a man, the greater part of these two cortlcosterolds were found in the urine in ester sulphate fraction. Evidence that sulphate was attached to C-21 was provided by the similarity of chromatographic behavior with that of authentic cortlcosterone 21-sulphate or cortlsol 21-sulphate, electrophoretic separation for cortlsol sulphate and the reaction to tetrazolium being positive only after hydrolysis.Keywords
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