The Incidence of Spontaneous Tumors in Female Mice (Breeders) of the CBA Strain

Abstract

The incidence of spontaneous tumors in female mice (breeders) of the CBA strain has been indicated in three recent papers (1–3). The purpose of dividing the observations into a series of individual experiments has been to eliminate any possible genetic variability as a source of varying tumor incidence. So far, two series (1, 2) of mice have been used for a moderate degree of breeding and then placed in reserve on a “mixed oatmeal diet”; a third series (3) of 63 females was similarly treated but continued throughout life on a commercially prepared diet.