Abstract
Immediate loss of toxicity of tetanus toxin is caused by treatment with Zephiran; pyocyanase inhibits the lethal effect after incubation for 24-48 hrs.; actinomycin A has no effect on toxicity of either tetanus or diphtheria toxins and tyro-thricin not only does not inhibit the toxicity of tetanus toxin but prevents loss of toxicity of both tetanus and diphtheria toxins on incubation.

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