Inhibition of Steroid Mediated Pyridine Nucleotide Transhydrogenase and 17 Hydroxysteroid Dehydrogenase by 2'Adenylic Acid.

Abstract
Summary 2'AMP inhibits placental 17 β hydroxysteroid dehydrogenase and steroid mediated pyridine nucleotide transhydrogenase. This inhibition is due to the 2'structure and occurs in transhydrogenation which does not involve TPN.