In the past few years a number of papers dealing with the question of nonspecific inflammatory lesions in the gastro-intestinal tract have appeared. Some of the papers dealt with the subject at length. Others reported only a few cases with comments. A great deal remains to be clarified, especially regarding the early phases of the disease. More specific information is needed relating to (1) prognosis as to life, (2) incidence of recurrence even after radical surgical intervention, and (3) the end-results in cases of the early stages noted at operation, in which no resection or other intestinal procedure is done. Criteria for clinical diagnosis must be established, as it becomes more obvious daily that the condition is not uncommon and must surely be noted from time to time in the routine experience of the general practitioner. He must be prepared to recognize the syndrome or at least the possibilities thereof.