The Specific Reduction of a and d Antigenic Determinants after Periodate Treatment of Hepatitis B Surface Antigen (HBsAg)
- 1 February 1978
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 38 (2), 363-367
- https://doi.org/10.1099/0022-1317-38-2-363
Abstract
Summary HBsAg antigenicity was found to be sensitive to periodate treatment. Antigenic determinants a and d were especially sensitive, losing almost all of their activity, while determinants r and w were found to be quite stable. Also, it is now possible to prepare the monospecific antibodies, anti-r and anti-w, by the use of this new, simpler procedure.This publication has 3 references indexed in Scilit:
- Carbohydrate Composition of Hepatitis B Surface AntigenJournal of General Virology, 1977
- Tryptic Cleavage of Antibody Binding Sites from Hepatitis B Surface Antigen ParticlesJournal of General Virology, 1976
- Specific cleavage of tryptophyl peptide bonds with periodate in sperm whale myoglobinArchives of Biochemistry and Biophysics, 1967