Different receptors for distribution of peanut and ricin agglutinins between inner and outer segments of rod cells

Abstract

Lectins can be used as probes for cell-surface oligosaccharides^1–4. These proteins display high specificities for certain haptene sugars, although the details of the sugar linkages and the three-dimensional array of the oligosaccharide may all be involved in determining the affinity of a lectin for its receptor. We have now shown that peanut and ricin agglutinins bind differentially to the surfaces of rod inner and outer segments.