IGE IN EXPERIMENTAL SCHISTOSOMIASIS .1. SERUM IGE LEVELS AFTER INFECTION BY SCHISTOSOMA-MANSONI IN VARIOUS STRAINS OF RATS

  • 1 January 1977
    • journal article
    • research article
    • Vol. 33 (4), 501-505
Abstract
Serum Ig[immunoglobulin]E levels were measured by radioimmunoassay in 4 strains of rats, before and after infection by S. mansoni. Differences were observed in basal IgE levels, depending on the strain considered. Serum IgE rose 10-20 days after infection and the maximum level, between days 30-50, ranged 14-60 times the basal level. One of the most characteristic features of IgE production in rat schistosomiasis was the persistence of high IgE levels for a long time after rejection of the worms.