The Effect of Flavoxate on Uninhibited Detrusor Contractions and Urinary Incontinence in the Elderly

Abstract
The effect of flavoxate, a smooth muscle relaxant, was investigated in 6 elderly patients with uninhibited detrusor contractions associated with urinary incontinence. Cystometry was done initially to confirm the diagnosis, immediately after an i.v. injection of 100 mg flavoxate and after 200 mg flavoxate orally 4 times daily for 7 days. No consistent drug effect could be detected cystometrically and incontinence was unchanged clinically.