Fungal metabolites. Part 5. Uvidins, new drimane sesquiterpenes from Lactarius uvidus Fries

Abstract

Uvidin A (IIa) and uvidin B (IIc) along with (–)-drimenol have been isolated from Lactarius uvidus Fries (Basidiomycetes). The structure and the stereochemistry of the two uvidins have been determined both by spectroscopic data and chemical reactions. Compound (IIa) has been correlated with (+)-drimanol (VIII) by transformations into (VI) and then (VII). Reactions and spectroscopic data are discussed.