Osteomalacia Due to Ileal Replacement of Ureters: Report of 2 Cases
- 1 February 1984
- journal article
- case report
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 131 (2), 335-337
- https://doi.org/10.1016/s0022-5347(17)50368-7
Abstract
We report 2 cases of ileal replacement of the ureters: 1 bilateral and 1 unilateral with a single kidney. Hyperchloremic acidosis developed in both patients and osteomalacia was proved by iliac bone biopsy. Patient 1 had symptomatic bone disease and control of acidosis with sodium bicarbonate was difficult because of associated hypertension. The level of alkaline phosphatase varied inversely with the level of serum bicarbonate. Pharmacological doses of 1-alpha hydroxycholecalciferol were ineffective and osteomalacia persisted in a second biopsy. Patient 2, who was asymptomatic, suffered acidosis and increased serum alkaline phosphatase levels immediately postoperatively and osteomalacia was confirmed histologically at 6 months.Keywords
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