Ring-substituted β-methoxyphenethylamines: a new class of psychotomimetic agents active in man
- 1 August 1985
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 37 (8), 575-577
- https://doi.org/10.1111/j.2042-7158.1985.tb03072.x
Abstract
Four members of a new class of psychotomimetic agents have been synthesized and evaluated in man. These compounds, which incorporate a β-methoxy group onto a β-phenethylamine sidechain, are the first reported psychotomimetics which are structural analogues of the neurotransmitter noradrenaline. These substances are more potent than the corresponding phenethylamines (lacking a β-methoxy group) but less potent than the correspondingly substituted amphetamine derivatives.Keywords
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