The self-administered SCL-90 [Symptom checklist] test was utilized to collect emotional distress data on 120 female patients requesting morning-after pill pregnancy interception. SCL prescores were significant in anxiety, guilt and depression factors. The 2 wk post-treatment results showed a significant decrease in these factors. This test provides reliable measurement of emotional distress factors in gynecologic patients. The results must be considered supportive for the use of DES [diethylstilbestrol] interceptive therapy in spite of other clinical considerations relative to its safety.