Synthesis of 2- and 6-deoxyinositol 1-phosphate and the role of the adjacent hydroxy groups in the mechanism of inositol monophosphatase

Abstract

The 2- and 6-hydroxy groups of myo-inositol 1-phosphate have been shown to be independently associated with the mechanisms of hydrolysis and binding in the dephosphorylation of the substrate by inositol monophosphatase.