The Anthelmintic Effect of Bephenium on Ancylostoma caninum

Abstract

Naturally infected dogs and cats harboring Ancylostoma caninum were given single doses of various bephenium salts in capsules. Those receiving over 20 mg/kg showed 99.4% clearance and those receiving 20 mg/kg or less lost 94.1% of their hookworms. In dosages of 50 mg/kg or over two-thirds of the Toxocara were killed, but only about one-fourth were eliminated at dosages of under 50 mg/kg. Bephenium showed definite activity against Physaloptera sp. and slight activity against Trichuris vulpis. The only side effects were occasional nausea and vomiting.