Effects of pimozide and bromocriptine on anterior pituitary cell proliferation
- 1 September 1978
- journal article
- research article
- Published by Springer Nature in Journal of Neural Transmission
- Vol. 42 (3), 239-244
- https://doi.org/10.1007/bf01675313
Abstract
The effects of pimozide (a dopamine receptor blocker) and bromocriptine (a dopamine receptor agonist) on the mitotic incidence in the anterior pituitary in male rats was investigated. It was shown that pimozide enhanced anterior pituitary mitotic activity in male rats. Bromocriptine, in turn, suppressed anterior pituitary cell proliferation in estradiol-treated male rats. A dopaminergic control of anterior pituitary mitotic activity is suggested.This publication has 12 references indexed in Scilit:
- EFFECTS OF PIMOZIDE AND BROMOCRIPTINE ON THE PROLIFERATION OF RAT PITUITARY PARS INTERMEDIA CELLSJournal of Endocrinology, 1977
- Effects of Estradiol-17β and Pimozide on Prolactin Synthesis in Male and Female Rats1Endocrinology, 1977
- Dopamine/Neuroleptic Receptors in Basal Hypothalamus and PituitaryEndocrinology, 1976
- Involvement of Catecholaminergic and Cholinergic Mechanisms in the Pulsatile Release of LH in the Long-Term Ovariectomized RatNeuroendocrinology, 1976
- Modifications of Striatal Dopamine Levels by Steroid Contraceptive Drugs in Mice and RatsNeuroendocrinology, 1976
- Dopaminergic Control of Adenohypophysial Weight and Serum Ceruloplasmin Level in RatsNeuroendocrinology, 1976
- Galactorrhea-Amenorrhea, Brom-Ergocryptine, and the Dopamine ReceptorNew England Journal of Medicine, 1975
- Effects of oestrogen and bromocryptine on in vivo secretion and mitosis in prolactin cellsNature, 1975
- Estradiol and the Neuroendocrine Control of LH Release in VitroEndocrinology, 1970
- Castration, Sex Hormones, and Tubero-Infundibular Dopamine NeuronsNeuroendocrinology, 1969