The Relaxing Effect of an Aqueous Extract of Glaucium arabicum on Uterine Smooth Muscle of Rat and Guinea Pig

Abstract
The effects of an aqueous extract of Glauciumn arabicum on uterine smooth muscle of rat and guinea pig were tested in vitro using isolated uterine horns. The aqueous extract of G. arabicum inhibited the spontaneous movement of the rat and guinea pig uterine smooth muscle. Also, the aqueous extract inhibited the contractions of rat and guinea pig uterine smooth muscle induced by oxytocin stimulation. This inhibition was dose-dependent and reversible. These data suggested that this plant extract has an antioxytocic effect.