Phospholipid Composition of Mitochondria and Microsomes of Liver and Kidney in Adrenalectomized, Hypophysectomized, and Diabetic Rats

Abstract

The individual phospholipid concentration of mitochondria and microsomes of liver and kidney in adrenalectomized, hypophysectomized, and diabetic rats was studied. Adrenalectomy and hypophysectomy resulted in a decreased concentration of total phospholipid of mitochondria and microsomes of liver and kidney. A decreased concentration of total phospholipids occurred in the microsomes of liver and kidney of the diabetic rats. This decrease of liver and kidney mitochondria and microsomes is apparently uniformly distributed in all of the phospholipid fractions except phosphatidylinositol. A decreased concentration of phosphatidyl-inositol of liver mitochondria occurred in the hypophysectomized rats.