Pentamidine-associated fatal acute pancreatitis
- 7 November 1986
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 256 (17), 2383-2385
- https://doi.org/10.1001/jama.256.17.2383
Abstract
Severe hemorrhagic pancreatitis developed in a patient with the acquired immunodeficiency syndrome (AIDS) during pentamidine isethionate treatment forPneumocystis cariniipneumonia. Despite prompt withdrawal of administration of the drug, the patient died of complications of pancreatitis. Pentamidine is known to be toxic to pancreatic islet cells, causing both hypoglycemia and hyperglycemia in clinical use. However, it rarely causes symptomatic pancreatitis. A review of the literature indicates that this is the second report of fatal pancreatitis associated with pentamidine therapy. (JAMA1986;256:2383-2385)This publication has 5 references indexed in Scilit:
- Pentamidine and PancreatitisAnnals of Internal Medicine, 1986
- Pentamidine for the Treatment of Pneumocystis carinii Pneumonia and Other Protozoal DiseasesAnnals of Internal Medicine, 1985
- Acute PancreatitisAnnals of Internal Medicine, 1985
- Pneumocystis cariniiPneumonia in the United StatesAnnals of Internal Medicine, 1974
- Pentamidine Isethionate in the Treatment of Pneumocystis carinii PneumoniaAnnals of Internal Medicine, 1970