Prolonged deterioration of ischemic brain energy metabolism and acidosis associated with hyperglycemia: Human cerebral infarction studied by serial 31P NMR spectroscopy
- 1 April 1988
- journal article
- research article
- Published by Wiley in Annals of Neurology
- Vol. 23 (4), 416-418
- https://doi.org/10.1002/ana.410230423
Abstract
We report on a patient with a large ischemic hemispherical stroke studied serially by 31P nuclear magnetic resonance spectroscopy. Persistent hyperglycemia was associated with prolonged acidosis in ischemic brain and failure of high‐energy phosphate metabolism to recover. These in vivo human data support the concept that hyperglycemia adversely affects ischemic brain metabolism, pH, and clinical outcome.This publication has 13 references indexed in Scilit:
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