MEASUREMENT OF THE EARLY THYROID CLEARANCE OF RADIOIODINE AS A CLINICAL TEST

Abstract
SUMMARY: 1. A method is described of measuring the early thyroid 'clearance' by the technique of Berson, Yalow, Sorrentino & Roswit [1952], with the results expressed as the percentage of extracellular fluid cleared per half hour. This measurement has satisfactorily segregated from a normal group: 10 out of 10 definitely and 11 out of 11 probably thyrotoxic, 11 out of 12 definitely myxoedematous and 1 out of 4 probably myxoedematous patients. The technique is relatively simple and rapid. 2. Measurement of the early thyroid clearance is closely correlated with the urinary 'T' index of thyroid uptake (for log values of each, r=0·90).