Metabolism of Radioactive DDT by the Madeira Roach and European Corn Borer12

Abstract

The absorption, metabolism, and excretion of p, p''-C14-labeled DDT was studied in the adult, female Madeira roach, Leucophaea maderae, and the 5th instar European corn borer larva, Pyrausta nubilalis. The Madeira roaches absorbed 98% and excreted 50% of the applied radio-activity in 36 days. Separation of the radioactive compounds excreted in the feces was accomplished by paper chromatography. The chromatograms were assayed with a GM tube. The presence of DDT, DDE, and 3 unidentified metabolites was demonstrated. Fifth instar European corn borer larvae possessed some tolerance to DDT and converted significant amts. of DDT to DDE. No evidence of DDT metabolites other than DDE was found.