Herbicolins - new peptide antibiotics from Erwinia herbicola.
- 1 January 1980
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 33 (4), 353-358
- https://doi.org/10.7164/antibiotics.33.353
Abstract
E. herbicola (strain A 111) produces 2 acylated peptide antibiotics, herbicolins A and B. Isolation of herbicolins was performed by adsorption on a polystyrol adsorbent followed by elution with methanol. Further purification was achieved by gel filtration on Sephadex LH-20, counter-current distribution or by TLC. Herbicolin A was chemically characterized, containing 2 glycines, 1 L-threonine, 1 D-allo-threonine, 1 D-glutamic acid, 1 D-leucine, 1 L-arginine and .beta.-hydroxy myristic acid. Herbicolins A and B are inactive against bacteria, but highly active against yeasts and filamentous fungi.This publication has 1 reference indexed in Scilit:
- Rapid Gas Chromatographic Separation of Amino Acid Enantiomers with a Novel Chiral Stationary PhaseJournal of Chromatographic Science, 1977