Susceptibility of multidrug-resistant isolates ofKlebsiella pneumoniae to silver nitrate

Abstract
Multidrug-resistant (MDR) clinical isolates ofKlebsiella pneumoniae were checked for their sensitivity toward silver nitrate by the tube-dilution method. Nearly 75% of MDR strains clould be successfully inhibited by 5 mg/L of silver nitrate. A significant correlation was observed between incidence of silver and trimoxazole resistance and silver and kanamycin resistance in these isolates. The genetic linkage of these two properties could not be proved since simultaneous curing and co-transfer studies gave negative results.