THE CENTRAL NERVOUS SYSTEM IN HEPATIC DISEASE
- 1 July 1949
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Neuropathology and Experimental Neurology
- Vol. 8 (3), 283-294
- https://doi.org/10.1097/00005072-194907000-00002
Abstract
The central nervous system in 8 out of 18 cases of severe liver disease revealed extensive alterations. The changes involved all regions of the brain and consisted of nerve cell damage and widespread areas of demyelination. The tissue alterations were predominantly perivascular in nature, suggesting a toxic etiology. From a review of the literature and a study of these cases it is felt that the liver damage enables some endogenous toxin to reach the brain and produce widespread damage.Keywords
This publication has 5 references indexed in Scilit:
- PATHOLOGIC ASPECTS OF ACUTE EPIDEMIC HEPATITIS, WITH ESPECIAL REFERENCE TO EARLY STAGES - REPORT OF A SERIES OF 10 CASES, INCLUDING A CASE IN WHICH THERE WAS SPONTANEOUS RUPTURE OF THE SPLEEN AND 6 CASES OF FULMINATING DISEASE IN PATIENTS WHO HAD BEEN WOUNDED SEVERAL MONTHS PREVIOUSLY1946
- HEPATITIS DUE TO THE INJECTION OF HOMOLOGOUS BLOOD PRODUCTS IN HUMAN VOLUNTEERS 1JCI Insight, 1944
- The pathology of fatal epidemic hepatitis1944
- SOME CLINICAL STUDIES OF ACUTE HEPATITIS OCCURRING IN SOLDIERS AFTER INOCULATION WITH YELLOW FEVER VACCINE; WITH ESPECIAL CONSIDERATION OF SEVERE ATTACKSAnnals of Internal Medicine, 1944
- PATHOLOGY OF CENTRAL NERVOUS SYSTEM IN DISEASES OF THE LIVERArchives of Neurology & Psychiatry, 1933