The Chromosome Complement of Human Solid Tumors

Abstract

INFORMATION about the chromosome complement of human tumors has been obtained from three sources: direct squashes of primary tumors; squashes of tumor cells in pleural or ascitic fluid; and squashes from cultured tumor cells. The relation of the abnormalities found with the latter two technics to the karyotype of the primary tumor is unclear, owing to possible selection of cell lines, and few karyotypes of primary-tumor squashes have been presented that can be evaluated in terms of the Denver Convention. It is the purpose of the present report, therefore, to report a modified technic for the study of human cancer . . .