Dental Caries in Rats Fed a Diet Containing Processed Cereal Foods and a Low Content of Refined Sugar
- 29 August 1952
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 116 (3009), 229-231
- https://doi.org/10.1126/science.116.3009.229
Abstract
Artificial caries in rats resulting from exptl. diets has not previously matched the pattern of normally-appearing caries in humans, appearing typically in the deep fissures of occlusal surfaces in the rats, and not (as in humans) on buccal, lingual, or proximal surfaces. Exptl. basal diet no. 586 (ingredients and directions for prepn. are given in detail) does not contain a coarse particle factor, and sugar content (18%) is low; it is deficient in cereal protein, particularly lysine, and results in a caries-pattern strikingly similar to that of humans. The rats (Holtzman strain) show high variability as to number of animals involved, number of teeth involved, and pattern of development in each tooth.Keywords
This publication has 11 references indexed in Scilit:
- The Caries-producing Capacity of Starch, Glucose, and Sucrose Diets in the Syrian HamsterScience, 1949
- Caries-Conducive Effect of a Purified Diet When Fed to Rodents During Tooth DevelopmentThe Journal of the American Dental Association, 1948
- Amino Acid Impairment in Casein Heated With GlucoseScience, 1948
- Observations on Induced Caries in RatsJournal of Dental Research, 1945
- Dental Caries in the Cotton RatJournal of Nutrition, 1944
- The Production of Carious Lesions in the Molar Teeth of Hamsters (C. auratus)Public Health Reports (1896-1970), 1942
- Relation Between the Physical Character of Food and Dental Caries in Albino RatsJournal of Nutrition, 1934
- Studies, in the Rat, of Susceptibility to Dental CariesJournal of Dental Research, 1933
- The Production of Dental Caries in Rats Fed an Adequate DietScience, 1931