Effects of Post-Operative Environment on Recovery from Dorsal Hippocampal Lesions in Young Rats: Tests of Spatial Memory and Motor Transfer

Abstract

Young rats (30 days old) were given dorsal hippocampal lesions and then housed in different conditions to assess the contribution of the environment to recovery from the effects of the lesion. They were subsequently tested on a spatial memory task and on a task requiring complex motor movements and transfer ability. Animals with lesions were inferior to sham-operates on both these tasks. Social housing and environmental enrichment improved performance on both tests, but there was no evidence for an interaction between lesion and environmental effects. The validity of using the term “recovery” in these circumstances is discussed, and called into question.