Maribavir Antagonizes the Antiviral Action of Ganciclovir on Human Cytomegalovirus
- 1 October 2006
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 50 (10), 3470-3472
- https://doi.org/10.1128/aac.00577-06
Abstract
The cytomegalovirus (CMV) UL97 kinase inhibitor maribavir antagonized the anti-CMV effect of ganciclovir, increasing the ganciclovir 50% inhibitory concentration against a sensitive strain by up to 13-fold. Antiviral activities of foscarnet and cidofovir were unaffected by maribavir.Keywords
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