APPLICATION OF RADIORECEPTOR ASSAY FOR HUMAN CHORIONIC-GONADOTROPIN IN PREGNANCY TESTING AND MANAGEMENT OF TROPHOBLASTIC DISEASE
- 1 January 1977
- journal article
- research article
- Vol. 50 (3), 324-332
Abstract
A commercially prepared radioreceptor assay (RRA) for human chorionic gonadotropin (hCG) was evaluated as a pregnancy test and in a quantitative assay to follow patients with hydatidiform mole. The RRA demonstrated almost 100% agreement in comparison with radioimmunoassay (RIA) and urinary hCG tests. In the quantitative assay, a limiting reliable concentration of 70 mIU/ml of hCG in serum could be obtained. Extremely good correlation was achieved between the RRA and RIA test for hCG in 2 patients with hydatidiform mole over a span of 3 mo. of followup after evacuation of the mole. The usefulness of the RRA as a replacement of RIA tests for hCG is discussed.Keywords
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