Microembolism in the Pathophysiology of Shock

Abstract

Platelet microembolism has been studied in experimental shock. Cinephotomicrographs have been obtained which demonstrate the emboli as they lodge in the lung blocking the circulation. There is a simultaneous elevation of venous pressure and drop of arterial pressure, as well as a drop in the systemic platelet count. It is felt that micropulmonary embolism may be a factor in the right heart failure and systemic hypotension often described in irreversible shock.