HIGH-DENSITY LIPOPROTEIN CHOLESTEROL AND MYOCARDIAL-INFARCTION OR SUDDEN CORONARY DEATH - PROSPECTIVE CASE-CONTROL STUDY IN MIDDLE-AGED MEN OF THE OSLO STUDY

Abstract

The high density lipoprotein (HDL) cholesterol concentrations of frozen specimen obtained in 1972-1973 from 93 men aged 40-49 yr who developed coronary heart disease (CHD) and for 186 controls are reported. Mean HDL cholesterol of CHD-patients was 7.9% lower than that of controls matched for smoking habits and serum concentrations of triglycerides and total cholesterol (P < 0.05 for 82 men who had myocardial infarction, no significant difference for all with sudden coronary death) and 10.2% lower (P < 0.05) than that of controls who are not matched for the parameters mentioned. Apparently HDL cholesterol is inversely associated with the risk of developing CHD in middle-aged men.