Foundation review: Principles and applications of LC-MS in new drug discovery
- 1 October 2005
- journal article
- review article
- Published by Elsevier in Drug Discovery Today
- Vol. 10 (20), 1357-1367
- https://doi.org/10.1016/s1359-6446(05)03620-2
Abstract
No abstract availableKeywords
This publication has 85 references indexed in Scilit:
- Investigating the human metabolism of acetaminophen using UPLC and exact mass oa-TOF MSJournal of Pharmaceutical and Biomedical Analysis, 2005
- A novel incubation direct injection LC/MS/MS technique for in vitro drug metabolism screening studies involving the CYP 2D6 and the CYP 3A4 isozymesJournal of Pharmaceutical and Biomedical Analysis, 2005
- Cell culture-based models for intestinal permeability: A critiqueDrug Discovery Today, 2005
- A method for the direct analysis of drug compounds in plasma using a single restricted access material (RAM) columnJournal of Pharmaceutical and Biomedical Analysis, 2004
- Whatever happened to cassette-dosing pharmacokinetics?Drug Discovery Today, 2004
- Automated high throughput ADME assays for metabolic stability and cytochrome P450 inhibition profiling of combinatorial librariesJournal of Pharmaceutical and Biomedical Analysis, 2004
- Comparison of conventional and enhanced mass resolution triple‐quadrupole mass spectrometers for discovery bioanalytical applicationsRapid Communications in Mass Spectrometry, 2003
- Enhanced resolution triple-quadrupole mass spectrometry for fast quantitative bioanalysis using liquid chromatography/tandem mass spectrometry: investigations of parameters that affect ruggednessRapid Communications in Mass Spectrometry, 2002
- Open‐access liquid chromatography/mass spectrometry in a drug discovery environmentJournal of Mass Spectrometry, 2002
- Peer Reviewed: Systematic LC/MS Metabolite Identification in Drug DiscoveryAnalytical Chemistry, 2001