Patterns of Failure in Patients with Resected Stage I and II Non-Small-cell Carcinoma of the Lung
Open Access
- 1 January 1987
- journal article
- research article
- Published by Wolters Kluwer Health in Annals of Surgery
- Vol. 205 (1), 67-71
- https://doi.org/10.1097/00000658-198701000-00012
Abstract
The pattern of failure was studied in 1012 patients with resected Stage I or II non-small-cell carcinoma of the lung. Initial intra-thoracic failure (41%) was more common than initial extrathoracic failure (34%) even though a complete resection was the intent in all patients. The most frequent sites of initial failure were the bronchial resection line (16%) and the central nervous system (CNS) (15%). The site distribution of initial failure does not appear to depend on TNM stage or pattern of nodal involvement. Patients with poorly differentiated disease had a greater rate of initial extrathoracic failure (pKeywords
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