Abstract
To the Editor: Mulley and colleagues* have concluded that screening followed by vaccination of susceptible persons in populations such as those of homosexual men would result in savings of medical costs and that neither screening nor vaccination would be cost effective in the general population.Their conclusion that vaccination without prior screening is the most cost-effective strategy for the protection of surgical residents may be analyzed further. For this population, in contrast to homosexual men and the general population, all three strategies yield similar cost-per-person estimates ($104 to $114). As noted in the authors' sensitivity analysis, however, when the prevalence . . .

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