CHEMICAL AND ENZYMATIC SYNTHESIS OF CARBAMYL PHOSPHATE

Abstract
An exposition is presented of the chemical synthesis of carbamyl phosphate (CAP) from cyanate and phosphate, and its decomposition, and the biochemical synthesis going by way of a carbamate phosphokinase transferring the terminal phosphate of ATP to carbamate. Evidence is presented to indicate that CAP is the intermediary in the car-bamylization of ornithine and aspartic acid in animal tissue as well as in microbial systems.

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