SODIUM-RETAINING CORTICOID IN THE URINE OF NORMAL CHILDREN AND ADULTS AND OF PATIENTS WITH HYPOADRENALISM OR HYPOPITUITARISM
- 1 September 1954
- journal article
- letter
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 14 (9), 1086-1089
- https://doi.org/10.1210/jcem-14-9-1086
Abstract
Urine was acidified to pH 1.0, allowed to stand for 24 hours, and extracted with chloroform. Na-retaining corticoid (probably aldosterone) was separated by chromatography and measured by bioassay. An average of 86 [mu]g DCA equivalent was found in 1 days urine of 5 normal adults. Children (4-8 years) excreted about 2/3 as much as adults. Two patients with panhypopituitarism had a normal output of Na-retaining corticoid, but insignificant levels were found in Addison''s disease or after surgical adrenalectomy.Keywords
This publication has 7 references indexed in Scilit:
- CHROMATOGRAPHIC SEPARATION OF THE SODIUM-RETAINING CORTICOID FROM THE URINE OF CHILDREN WITH NEPHROSIS, COMPARED WITH OBSERVATIONS ON NORMAL CHILDREN 12Journal of Clinical Investigation, 1954
- BIOASSAY OF ADRENAL CORTICAL STEROIDS ON THE BASIS OF ELECTROLYTE EXCRETION BY RATS: EFFECTS OF 11-DESOXY and 11-OXY-STEROIDS1Endocrinology, 1954
- METHOD OF ASSAY OF A SODIUM-RETAINING FACTOR IN HUMAN URINE1Endocrinology, 1953
- Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissuesBiochemical Journal, 1952
- PAPER CHROMATOGRAPHY OF STEROIDS .2. CORTICOSTEROIDS AND RELATED COMPOUNDS1951
- A morphological and histochemical study of the rat's adrenal cortex after hypophysectomy, with comments on the liverJournal of Anatomy, 1946
- Simmonds' Disease. A Clinical Study with Review of the Literature; Differentiation from Anorexia Nervosa by Statistical Analysis of 595 Cases, 101 of Which Were Proved Pathologically1Journal of Clinical Endocrinology & Metabolism, 1942